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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4682fc60dee78150c000226c178386dd7fe815e021e1ecedd30ecf2743e25911' 
  AND token = 'AN91qDcTZ/7ytKiwAkwbHnXruwUBN1zB0z3dJ923vzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}