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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38e5c48f3647e143f51b19e0833a579e3ae89f6c3db2e88a9b49546ec7e0686' 
  AND token = 'DSOOyii9L8hl8MkFMVrXnSqdEVDhO/T78Ytril7XPZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}