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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aee1f7b435b3dc0af0a4d98cfbd57499d856793c89d2b36b064affe1f2bcafe1' 
  AND token = 'Fc645FCdtoH3GBmvcHYUzcdRUa6ilzY0wvBqm3jqUm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}