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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '733f13632143aefffa34b52ac40c5bcc099e620275356d81c415345dbb0faa18' 
  AND token = '1l0jmeeZNmx48awAHMLXW/reNCu1zK6vp/2jNXRATDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}