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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49095e1617a220a52e07427df880202c94d3842802b8245ce46470b48e72441e' 
  AND token = 'aqqRHejSDyaCRmSCfh8BNIX3fadm8r/T9IWZgEvLOpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}