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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bbdede65fe96c77e31a4a58d940dce81fe3ce54d3e6f862c279246a161c49cd' 
  AND token = 'hUXu6Wbt/8ok0/A9S65Akzjo+PAn8HxwVYh0ShUYVGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}