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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13d0dde1f782388c7658c078127e7927e8935f2f7b2da2919c1ccb46cb3ba325' 
  AND token = 'g2OSVMOdg0Tu+LAe16lJZWt8kxLyTN+M0GrSHO1TYoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}