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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6679bbbbef6ccc7024de6ed158456f08d2d10f8a4bc7976894052c7d1e5e6de1' 
  AND token = 'eUTlOlOZYwM+VOIzBeG1TABSfRLpWa3JujuTbdfta/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}