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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bfdcb2da371f7cbb0cac27cbb2e9dfdece37594db64226d2c3c07a7be7a7f77' 
  AND token = 'F5mlA9trzZaxNqsR7CRi2uGe9W2iKboWBe7C7Jjf2pI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}