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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cc396e41285f484730e050a4c574a90c0b99651470bb40123b5594f3c5d0199' 
  AND token = 'CIO/+5EWExfSPU/XDosc4pppY2SYUVi0Iy16jfYe8/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}