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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec78f8e3bff4203159062eab32138aa0c3cc6ba0340b337100a75e8714b97815' 
  AND token = 'SqvXbrNL3BuGDhM9rYzXOUO2n0h1o0PlDdiZSkf+8/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}