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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63c8776758cddc20d5278d371d7a6c24b889426cc1ed32ed0e8370769dc27f1e' 
  AND token = 'ADBLsJAXg8hw72CZ2r7dbVovbdSdCA3jFyZwG0qJPg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}