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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd375e6e696d1d1722539ddf696a49cb68fa8ae1746c833e22fe21c42dc0c081b' 
  AND token = '8fOWLwxCEKPtyYdWfGMO2VWe2kxtCJrnZIg4jo8t/sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}