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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c41ca31174bc2c31567789f52ad1cae4585c5e1ef00aaed818ad81cc6562f96' 
  AND token = '2HcE8Ko2HnYn1n1h3tbaFZ63yo4Q98PHyEm9QFl1jMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}