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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a99dc21982bb4cf2c2d3eaddd352884af40a97afc9c43b19ba2564b5b287377' 
  AND token = 'y3Hmzlec3UkfP+bYhXjndnsIYcGVP2EAZ+sM0sz7eEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}