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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae59c54b26fd31ec7830565209ad7ce8a9d8809e22a3544704f4fa5b555b0b33' 
  AND token = '/6D1wifQzi4laTDdQgb3QXRFQtGvz9ZdVdqLU8E0Aqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}