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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b086d0033ced68e67054050b89c87d8b5b4f567564ee5c5f8c4c9248dd72a40' 
  AND token = 'GJt9isfxE8Oj13Vto3Fh7d9lJqxV3B/OjMxhyAhkLG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}