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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb6510d790f1e6d2536a59fffe171d060b105a4a5b5ce76be23e33e05a9f7555' 
  AND token = 'mvIPin96NrdOBcJAdta/Vx17jBc4NjAPq3b5Yjqd97U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}