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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f327a8e36584c8d1eed4f1d7477bd12bd088b00300233f13cad70bc9a95dc6' 
  AND token = 'itQCZxXrmIYn2hFBOIUrl+xm8z0Bu6E61GHW3p/0dmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}