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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2371e0090344a47575aa83fcce45346203bce2aebfbfa423e9304043422e55e9' 
  AND token = '1wFkqREWP4lNKQ+LjXOlPU3lU+kbv4vd5i3Mehm8Uwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}