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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd48900fa6c37ebea7a166ca9b5c81a6d920f8cce1611a0c8469b37bb205a200' 
  AND token = 'oZcDsS0l0+g9X3a2swncqqi6G0k3oehVMHPGTQRAyQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}