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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8263b5ace3e5cc71fa2d06b319b6edc3ef53f0e41605f7ef5aaecf40dfa2f5' 
  AND token = 'UGlyOPJo0Mxu+Ge4hsKmWAc3aKfXJfErW+mMwsrCJkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}