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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd48eb54153317cca7472c74580a4585b3e12a5fc111fb76c14b8253f0e00a51b' 
  AND token = 'drj8/czfi6R8ww3lxyEPEMgp1vA5LrfCl9qClg3cbz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}