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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e21e3f0f8f15ceb1d39f2c99050afc960d9ae1d5631f1e2f0f8fb8011f67ea' 
  AND token = 'yTa38QGNrhzcMFOariRHwoB/8MI2kGsG7nWrWrC0AZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}