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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b435dabb492533901f635bd5a070769afb32587599767598b27194cd7e4336a7' 
  AND token = 'EpfmXCwGWoKqkyJHpvZiAtCI1S3YgvoE7dsMPo4ONLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}