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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd44121e19eb95ca400930e713efc32608d99a2a28715ce6f8a252cbe279e79c1' 
  AND token = 'no3hW6BZ4dh/WTFLlTuU/yNhbxsp41U58vEUS3JXsb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}