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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32944d736d419a0e56e7d3882eaff793f158774658589ddcac8db66e4442a20f' 
  AND token = 'HC/HwhfLB6GOCGldv5sOdpPOMFMsMKK7qe80AbJHp6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}