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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cd8f601e66efa385de6aea54e9c9bfc14cf46b14a5faa460f807bc43cefce0d' 
  AND token = 'jj0Kkdmbkt8ctED5Z79JWavs6qK7GmcCa0IRfV3ZsS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}