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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd0f87a06f6470f64f4d731641ca8f36e7bcb1f89069060d6b6c9105a09b28e2' 
  AND token = 'Kviurqs17i+2rhHgHQWBaMQiqdXQbDmDjdoKiEZiEtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}