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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14784a137a83606a21ef581472765d340208e52476708564262feedc05d1022e' 
  AND token = 'ka33kZkCadWWifnJaBY/8uEGGrvrtU3P3Tkw6/CDBlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}