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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b9aa8f74c4f6cf6ec164b2f60acdbed7ebf2e6ba4a27a40304e3387313e2258' 
  AND token = 'TI2ZNKnTT05njtK+CHR3yC9F42SrgsJBckflKoHmNNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}