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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e332bf478fc5c5431af20c31fd895f5bce7392c6fb48eb0652c9fe9d507525c' 
  AND token = 'edCN6rwWF03a0Wmuf1xW9vxcH6n3u+z3kG6EZlsYb1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}