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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c9f3055c45540c9f1034a2b165da6b53aed43490247e9462317bc1cf552c517' 
  AND token = '+1yVqAxh18DdsWFLSiS6kioDLoO9Sk69Bsd+WLLCugk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}