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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d048e41a6c765fc244be6d9d6433ce5ef219976a522294ddb02fc1e830ac0ce' 
  AND token = 'KZFTkkBN6kuKV2uSENgs+iIryLvH6oHyc/d6zR6mhqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}