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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a38f09c4db4e64973a5167b7b47537fcdebba39de49de8672201fd0fae0580cc' 
  AND token = '0yHMT8aYBuTu6CdgTmtwuO3WaASICdFEyEkqImM7Rr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}