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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b2c5b2f11d10aeb3f1051cd0a99e0e566bf6cb8ad0a683486fdeec43e481a6' 
  AND token = 'HSzhtZLEAPq+1ydY0oYWMTo6AK1kjfe/B1o5s8vr658=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}