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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50431babb7d3864b9a605fb70fa7e44690d7c9a0eb18004f4dece4d63c722be8' 
  AND token = 'eEen2IGCrGLws0cmW0dma8R41OYJgRnHiN/c7rzskEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}