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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8f91c4fbe89494231313a3835b4fbd5c8af3da7221560e089b9761c3228d979' 
  AND token = 'Wwd8OQN2k+WFsoNeALWboyk+4oMp/KRh+MOOc93mLeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}