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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54a46bddcfb4b512ca3b7903ed440a5d2c99d5d8c7b53f0d1247167094adf19a' 
  AND token = 'E+A1R4dKu0qDEefkGMiHEY8xmFcYNenDLI0yjADoILU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}