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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19189ed1a5e1945013650a6ce37550ddef64d8a2ccf2381fe4540e3061936fca' 
  AND token = 'd/4/UhDcWyGfvfPNw4Vzn0zISrCFbc9MgDamQqJUMNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}