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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc7a99cb6b626fd883af3f849dd9306ca7dc2c1d8aae3158d0e570932c1d9fe' 
  AND token = 'YtVD+cShB7pM6LxAi6piWq1RNZo38sB0DVKQLlAWdew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}