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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c73198f68f18da05b7870d05c9ca58383b55a5e8d6f1fce958ddaf7d58bb899f' 
  AND token = 'eDlOc5e5EBsy9+IWL2n6gPRgzxAcpDpyQxml6CRvqfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}