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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d7a8a4998760c407a8b3d5812eddf82004fd407696050c11449875d05fa14f' 
  AND token = 'CGdwr+abahrsUFW/zQ/bMrijlt4/FzqW5udtmxFHSgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}