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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b0fcd7670157b5f67754e496ef6c577dea83998d3e6993b6e655d6245a99831' 
  AND token = '3xZ0XQIc1vzBlG9XgZPcXEAdV8ouRs6X5ee5QuDN3pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}