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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b54467734dd03b197ce9555f9a962765c689a8ac0b499b5c6c495a71210e5da' 
  AND token = '8YUAzftsRB3lNXRT3f6sBaNaSdhlqkEwsdT/jO0PRV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}