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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00da2aa3399a56d5effaafdfe6e37ace973bdd27977db327d1aa9e7758e5d486' 
  AND token = 'cclsCpfqNUg1VAgSMUsyr2YxN/auU5G9DVzLnbrfA+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}