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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f86dd4977e45e33ac71fa9ccc1ef8667ab339136987586134d99750bab9ab50d' 
  AND token = 'oCRcpsK7UV14HCgRKYEb5sW1X5/Y2k1NR084MKC/MQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}