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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8b606d6b3f4f98b36c679dd0bc7fc575eae38d31029802519508c18d249cca1' 
  AND token = 'EDnUTj7sB/lH1SHAUc100tYj46WNYULzpQyeWqNIvi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}