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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f90d16b9ae152f88b0cc05a26777a51e63d371ac16009e4e9d92785085c9a35' 
  AND token = 'nTWTZs3DZfaj8jQvhNP1/txtQhD0UkmKdcvJDZb9ee8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}