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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ccfcc8d56f69b75a2bc76e7f294c01aa2b5f0c90a452c676c6ca5778073c233' 
  AND token = 'FJ+eJbYJaVixVaCbBwjZv08G990aS0YH2FbXCEoxr6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}